Journal Of Tropical Biosciences
Volume No: 10|
Page No: 1
| FullText PDF
Title: PHYTOCHEMICAL SCREENING AND ANTIMICROBIAL ACTIVITIES OF THE METHANOLIC LEAF EXTRACT OF JACARANDA MIMOSIFOLIA D. DON AND SANSEVIERIA LIBERICA THUNB
1-ADELANWA, E.B. 2- AND ISMAIL HABIBU.
BIOLOGICAL SCIENCES DEPARTMENT,&NBSP;AHMADU BELLO UNIVERSITY, ZARIA.
In this study, the phytochemical screening and antimicrobial activities of the methanolic leaf extract of Jacaranda mimosifolia D. Don (Bignoniaceae) and Sansevieria liberica Thunb (Asparagaceae) were carried out. The phytochemical screening revealed the presence of carbohydrate, flavonoids and cardiac glycosides; absence of anthraquinones and alkaloids in both plants. However tannins, saponins and steroids were present in J. mimosifolia which were found to be absent in S. liberica but there is the presence of triterpenes in S. liberica. The methanolic leaf extracts of these two plants were also subjected to antimicrobial screening in accordance with agar well diffusion method. The extracts were tested against clinical isolates of Escherichia coli, Salmonella typhi, Bacillus cereus and Staphylococcus aureus with ciprofloxacin as a positive control. The zone of inhibition, Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) were determined. The result showed that all the test organisms were sensitive to the standard drug (control) as well as the methanolic leaf extract of J. mimosifolia though varied at different concentration of the extract. The result also showed that Bacillus cereus and Staphylococcus aureus were sensitive to the methanolic extract of S. liberica while Salmonella typhi and Escherichia coli were resistant to the extract.
The study concluded that the methanolic leaf extract of J. mimosifolia is active against both gram positive and gram negative bacteria of E. coli, S. typhi, B. cereus and S. aureus. Hence the extracts from these plants could be constituted as basic ingredient for the development of drugs that will cure infectious diseases caused these bacteria such as severe nausea, skin infections, dysentery, typhoid fever and some urinary tract nfections.
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